Hi bros and broettes, i rarely post here but ive been a member here for 15+ years.
^^^hey brother ..15+ yrs?? ..ok, i'll try to help
Questions: i take propecia.
^^^how much Propecia are you taking? ..just curious
1)If i take anavar and propecia simultelaneously, will it speed up my hairloss?
^^^the rationale here is that ANAVAR is a DHT derivative ..& therefore "automatically" causes hair loss
BUT this is not necessarily true
..just bc something is a DHT derivative does not mean that it has the same affinities for select tissues (..like scalp & prostate ..& things like SHBG) as actual biological DHT itself
..now that said; ..some of these "DHT-derivatives" may be able to potentiate hair loss
→ "IF" they have affinity for the scalp tissue themselves (..in other words; directly)
&/or..
→ "IF" they bind SHBG
why?
..bc SHBG binds different sex hormones with different affinities
SHBG binds; from greatest affinity to least affinity; in the following sequence:
DHT → TEST → Androstenediol → Estradiol → Estrone.
..DHT binds to SHBG with 5 times the affinity of TEST +/-
..& roughly 20 times the affinity of Estradiol
^^^so if a "DHT derivative" binds well to SHBG, then it could potentiate hair loss simply by occupying SHBG & freeing-up actual DHT
2)What about if i take propecia and dbol simultaneously?
^^^DBOL is a TEST derivative (..an analogue of TEST)
..though DBOL can be converted by 5α-Reductase into Methyl-1-Testosterone
..it has a very low propensity to do that
..DBOL also has a low affinity for SHBG (..about 10% of that of testosterone & 2% of that of DHT)
^^^so if you gonna go the route that "Propercia decreases DHT & therefore promotes hair loss"
..or in other words that "DHT is the sole cause of hair loss"
◄then i don't see the pathology with DBOL
►IMHO ..which includes blood work i'v seen over the years:
1.) most guys on TRUE TRT TEST doses have DHT levels that are "High-Normal" ..or just plain "High ..Out of Range"
2.) who runs these drugs without TEST? ◄no one
3.) most of us run much higher TEST doses ..even when we cruise
^^^well if you able to add all that up you'll see that the moral of the story is that it doesn't take much TEST to cause Supra-Physiological levels of DHT in the vast majority of men
(..TEST converts to DHT at a higher rate than it converts to Estrogen)
SOUND WILD??
..not really ..not when you consider that TEST is always there & that it does not take much (..or too long) to elicit these effects in the prone
(..& even in the non-prone ..it still does it ..just takes a bit longer before it's noticeable)
..& that we know for sure that biological DHT
DOES have great affinity for those tissues
^^^so YES ..from what i'v seen/know; i'm suggesting that "TEST" is the real "main" culprit
..& the UN-convicted criminal who is largely responsible for the crime of hair loss
..the blame of which some innocent DHT derivatives have received the undue brunt of
..
BUT that DHT derivative are not completely blameless ..even if they do not target the scalp (..& other tissues that biological DHT targets)
..why?
..bc they can potentiate liberation & bioavailability of any existing DHT (..& as we discussed above ..that can be a lot even on a True TRT dose)
.